A2M (alpha-2-macroglobulin) is a blood protein that can bind enzymes associated with cartilage breakdown. At NexGenEsis Healthcare San Antonio, A2M injections are offered as a targeted biologic option for certain patients with degenerative joint discomfort.

How A2M Therapy Works

• A blood sample is processed to concentrate A2M
  
• The A2M-rich solution is injected into the affected joint (often the knee) under guidance
  
• The goal is to neutralize cartilage-damaging enzymes, support remaining cartilage, and potentially reduce pain
  

Results vary by patient; it is not a guaranteed solution.

Who Might Be a Candidate

We may consider A2M injections if you:

• Have mild to moderate osteoarthritis with persistent symptoms
  
• Are exploring biologic options besides standard steroid or hyaluronic acid injections
  
• Understand that benefits, if present, may be modest and variable
  

We will compare A2M with other choices—PRP, BMAC, viscosupplementation, steroids, and non-injection strategies—so you see the full landscape.
If you’re reviewing injection options for arthritis in San Antonio, book a visit at NexGenEsis Healthcare to discuss whether A2M fits into your treatment strategy